Synthesis of Steroidal Thioethers via [HDBU][OAc]‐Mediated Michael Addition of Thiols to 16‐Dehydropregnenolone
Lilla Maksó, Krisztina Kovács, Kitti Andreidesz, Ágnes Gömöry, Sándor Mahó, Rita Skoda‐Földes ChemistrySelect, 2022, 7(29), e202200967, https://doi.org/10.1002/slct.202200967 In the catalytic addition of thiols to 16-dehydropregnenolone fourteen thioethers were prepared via thiol-Michael addition reaction in the presence of different aliphatic and aromatic thiols as reagents. [HDBU][OAc] was proved to be an efficient catalyst and solvent providing […]
Recyclable supported Brønsted acidic ionic liquid catalysts with non-aromatic cations for the oligomerization of isobutene under mild conditions
Júlia Fütyű, Dávid Ispán, Csaba Fehér, Ágnes Szegedi, Tatjána Juzsakova, Jenő Hancsók, Rita Skoda-Földes Molecular Catalysis, 2022, 518, 112075., https://doi.org/10.1016/j.mcat.2021.112075 Brønsted acidic ionic liquids with different type of cations (pyridinium, morpholinium, pyrrolidinium, imidazolium), N-sulfoalkyl chain length and different anions (triflate, hydrogensulfate and tetrafluoroborate) were prepared and immobilised on silica by adsorption. The ionic liquids were characterised […]
A Temperature-Controlled Switch between Fürst–Plattner Rule and Anti-Fürst–Plattner Rule Ring Opening of 2,3-Epoxy-steroids with Various Halide Sources in the Presence of Imidazolium Ionic Liquids
Anita Horváth, Kristóf Bolla, Alexandra Wachtler, Lilla Maksó, Máté Papp, Sándor Mahó, Zsófia Dubrovay, János Kóti, Rita Skoda-Foldes ACS Omega 2021, 6, 41, 26846–26856., https://doi.org/10.1021/acsomega.1c02470 The ring opening of 2α,3α- and 2β,3β-epoxy-5α-androstan-17-one with halide reagents (AlCl3, TMSCl, LiCl, and LiBr) was investigated using imidazolium ionic liquids in the dual role of solvent and catalyst. The application […]
Claisen‐Schmidt Condensation and Domino Claisen‐Schmidt Condensation‐Michael Addition of 16‐Formyl Steroids in the Presence of Switchable Polarity Solvents
Dávid Ispán, Bence Varga, Szabolcs Balogh, Balázs Zsirka, Ágnes Gömöry, Rita Skoda‐Földes ChemistrySelect, 2021, 6, 23, 5705-5710., https://doi.org/10.1002/slct.202100886 Switchable polarity solvents (reversible ionic liquids) have been used to replace conventional catalysts and solvents in Claisen-Schmidt condensation reactions of 16-formyl steroids and aromatic ketones. The primarily formed α,β-unsaturated ketones may undergo a Michael addition with the […]
Double carbonylation of iodoarenes in the presence of a pyridinium SILP-Pd catalyst
Béla Urbán, Enikő Nagy, Petra Nagy, Máté Papp, Rita Skoda-Földes Journal of Organometallic Chemistry2020, 918, 121287. The efficiency of a palladium catalyst, immobilised on a supported ionic liquid phase (SILP) with adsorbed 1-butyl-4-methylpyridinium chloride, was investigated in aminocarbonylation reactions. Double carbonylation was found to be the main reaction using different iodoarenes and aliphatic amines as […]